2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenol
Introduction
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenol, CAS 779331-13-4, is an organoboron compound used primarily as a chemical building block for research and organic synthesis.
The compound has the molecular formula C₁₃H₁₆BF₃O₃ and a molecular weight of approximately 288.07 g/mol. Its structure combines a phenolic group, a trifluoromethyl substituent and a cyclic pinacol boronate ester
What is CAS 779331-13-4?
CAS 779331-13-4 identifies 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenol.
| Property | |
| CAS Number | 779331-13-4 |
| Molecular Formula | C₁₃H₁₆BF₃O₃ |
| Molecular Weight | 288.07 g/mol |
| Compound Class | Organoboron / boronic ester |
| Typical Use | Research and organic synthesis |
These identifiers are consistently reported by chemical databases and commercial chemical suppliers.
Why is this boronic ester useful in organic synthesis?
The molecule contains a pinacol boronate (Bpin) group, a functional group widely used in modern synthetic chemistry. Pinacol boronic esters are particularly useful because of their practical stability and their compatibility with carbon-carbon bond-forming transformations.
One important application of organoboron compounds is the Suzuki-Miyaura cross-coupling reaction, in which an organoboron reagent can participate in the construction of new carbon-carbon bonds. This reaction has become an important tool for preparing structurally complex organic molecules.
The presence of both a trifluoromethyl (-CF₃) group and a phenolic hydroxyl group also makes CAS 779331-13-4 an interesting intermediate for the synthesis and diversification of substituted aromatic compounds.
Frequently Asked Questions
What is the CAS number of 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenol?
=> The CAS Registry Number is 779331-13-4.
What is its molecular formula?
=> Its molecular formula is C₁₃H₁₆BF₃O₃.
What is its molecular weight?
=> The molecular weight is approximately 288.07 g/mol.
What is it used for?
=> It is mainly relevant as an organoboron research building block and synthetic intermediate. Boronic esters are commonly employed in transformations such as Suzuki-Miyaura cross-coupling.