Produit
CAT:
CCP1370-01
Taille:
1 mg
Prix:
Connecter vous pour voir le prix
Qty:
Disponibilité et expédition
- Articles en stock livrables sous 24 à 48 heures et articles hors stock livrables sous 2 à 6 semaines
- Glace carbonique: Non requis
Description du produit
Peptide to PACAP (1-38), Human, Ovine, Rat
Propriétés du produit
Dangereuxnon
Glace carbonique requisenon
Marque déposéenon
Informations complémentaires
Cas: 124123-15-5
Structure Composition: H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Alternative Name: Pituitary Adenylate Cyclase Activating Polypeptide-38 (human, mouse, ovine, porcine, rat)
Applications: Kojro et al. observed that the PAC1 agonists PACAP-27 and PACAP-38 strongly increased the activity of α-secretase. Upregulation of this APP-degrading enzyme promotes the non-amyloidogenic processing of APP, i.e. reduces the production of Aβ40/42, and thus may help to prevent Alzheimer’s disease. Nasally applied PACAP-38 in APP[V717I]-transgenic mice additionally enhanced the production of the Aβ-degrading enzyme neprilysin via induction of somatostatin.
Purity: > 95%
Form: Lyophilized powder
Molecular Formula: C203H331N63O53S
Molecular Weight: 4534.36
Conditions de stockage: Shipped at 4°C. Store at -20°C for one year.
Light Source: Synthetic
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