Produit

CAT:
CCP1720-01
Taille:
1 mg
Prix:
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Qty:

Disponibilité et expédition

  • Articles en stock livrables sous 24 à 48 heures et articles hors stock livrables sous 2 à 6 semaines
  • Glace carbonique: Non requis
[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P

Description du produit

Peptide to [D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P

Propriétés du produit

Dangereuxnon
Glace carbonique requisenon
Marque déposéenon

Informations complémentaires

Cas: 96736-12-8
Structure Composition: D-Arg-Pro-Lys-Pro-D-Phe-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2
Applications: [D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P initially described as a low potency ghrelin receptor antagonist has surprisingly been found to be a full inverse agonist (EC50 = 5.2 nM) . In COS-7 cells transiently transfected with the ghrelin receptor the substance P analog rPKPfQwFwLL decreased the constitutive signaling down to levels observed in untransfected cells. Assuming that constitutive signaling of the ghrelin receptor is of physiological relevance in the regulation of appetite control, inverse agonists of the ghrelin receptor could be interesting for the treatment of obesity.
Purity: > 95%
Form: Lyophilized powder
Molecular Formula: C79H109N19O12
Molecular Weight: 1516.87
Conditions de stockage: Shipped at 4°C. Store at -20°C for one year.
Light Source: Synthetic

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