Produit
CAT:
CQA8408-01
Taille:
30 μl
Prix:
Connecter vous pour voir le prix
Qty:
Disponibilité et expédition
- Articles en stock livrables sous 24 à 48 heures et articles hors stock livrables sous 2 à 6 semaines
- Glace carbonique: Non requis
Description du produit
Mouse monoclonal antibody to AKT
Propriétés du produit
Dangereuxnon
Glace carbonique requisenon
Marque déposéenon
Informations complémentaires
Alternative Name: AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta; AKT3; PKBG; RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2
Reactivity: H, M, R
Immunogen: Purified recombinant human AKT1 protein fragments expressed in E.coli.AKT1 interacts (via the C-terminus) with CCDC88A (via its C-terminus) . Interacts with GRB10; the interaction leads to GRB10 phosphorylation thus promoting YWHAE-binding By similarity. Interacts with AGAP2 (isoform 2/PIKE-A) ; the interaction occurs in the presence of guanine nucleotides. Interacts with AKTIP. Interacts (via PH domain) with MTCP1, TCL1A AND TCL1B. Interacts with CDKN1B; the interaction phosphorylates CDKN1B promoting 14-3-3 binding and cell-cycle progression. Interacts with MAP3K5 and TRAF6. Interacts with BAD, PPP2R5B, STK3 and STK4. Interacts (via PH domain) with SIRT1. Interacts with SRPK2 in a phosphorylation-dependent manner. Interacts with RAF1. Interacts with TRIM13; the interaction ubiquitinates AKT1 leading to its proteasomal degradation. Interacts with TNK2 and CLK2. Interacts (via the C-terminus) with THEM4 (via its C-terminus) . Interacts with and phosphorylated by PDPK1.AKT2 interacts (via PH domain) with MTCP1, TCL1A AND TCL1B. Interacts with CLK2, PBH2 and TRAF6. AKT3 interacts (via PH domain) with TCL1A; this enhances AKT3 phosphorylation and activation. Interacts with TRAF6.
Clonality:
Monoclonal
Source: Mouse
Applications: WB, IP
Purification: The antibody was purified by immunogen affinity chromatography.
Dilution: WB (1/500 - 1/1000), IP (1/10 - 1/50)
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Conditions de stockage: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Specificity: Recognizes endogenous levels of AKT protein.
Ncbi Gene Symbol: AKT1; AKT2; AKT3
Swissprot Human: P31749; P31751; Q9Y243
Swissprot Mouse: P31750; Q60823; Q9WUA6
Swissprot Rat: P47196; P47197; Q63484
Entrez Gene Human: 207; 208; 10000
Entrez Gene Mouse: 11651; 11652; 23797
Entrez Gene Rat: 24185; 25233; 29414
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